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Published on: 2014-02-05
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Original language: English

Modern crystallographic methods originate from the synergy of two main research streams, the small-molecule and the macro-molecular streams. The first stream was able to definitively solve the phase problem for molecules up to 200 atoms in the asymmetric unit. The achievements obtained by the macromolecular stream are also impressive. A huge number of protein structures have been deposited in the Protein Data Bank. The solution of them is no longer reserved to an elite group of scientists, but may be attained in a large number of laboratories around the world, even by young scientists. New probabilistic approaches have been tailored to deal with larger structures, errors in the experimental data, and modest data resolution. Traditional phasing techniques like ab initio, molecular replacement, isomorphous replacement, and anomalous dispersion techniques have been revisited. The new approaches have been implemented in robust phasing programs, which have been organized in automatic pipelines usable even by non-experts. Protein structures, which 50 years ago could take months or even years to solve, can now be solved in a matter of hours, partly also due to technological advances in computer science.This book describes all modern crystallographic phasing methods, and introduces a new rational classification of them. A didactic approach is used, with the techniques described simply and logically in the main text, and further mathematical details confined to the Appendices for motivated readers. Numerous figures and applicative details illustrate the text. (IUCr) Texts on Crystallography IUCr Texts on Crystallography . ... Phasing in Crystallography - A Modern Perspective by ... The International Union of Crystallography is a non-profit ... (IUCr) - Phasing in Crystallography: A Modern Perspective ... IUCr IT WDC. ... Highlighting Dictionary of Crystallography IUPAC Gold Book more ... ... RefMan: Refer: Medline: CIF: SGML: Plain Text: Article statistics. Share ... Phasing in Crystallography: A Modern Perspective / AvaxHome Phasing in Crystallography: A Modern Perspective (Iucr Texts on Crystallography) by Carmelo GiacovazzoEnglish ... Phasing in Crystallography: A Modern Perspective ... Phasing in Crystallography eBook by Carmelo Giacovazzo ... Read Phasing in Crystallography A Modern Perspective by Carmelo ... A Modern Perspective ... International Union of Crystallography Texts on ... Phasing In Crystallography: A Modern Perspective (Iucr ... (International Union of Crystallography Texts on A Modern Perspective (Iucr Texts on ... main text is dedicated is indeed a modern perspective of phasing in Phasing in crystallography: a modern perspective Phasing in crystallography: a modern perspective on ResearchGate ... IUCr Texts on Crystallography ... International Union of Crystallography/Oxford University ... Phasing in Crystallography a Modern Perspective (Iucr ... Phasing in Crystallography a Modern Perspective. Browse. Interests. Biography & Memoir; Business & Leadership; Fiction & Literature; Politics & Economy; Health ... Phasing in crystallography : a modern perspective (Book ... Phasing in crystallography : a modern perspective. ... International Union of Crystallography texts on ... name " Phasing in crystallography : a modern ... Phasing in Crystallography: A Modern Perspective. By ... Phasing in Crystallography: A Modern ... IUCr Texts on Crystallography No. 20. International Union of Crystallography/ Phasing in Crystallography - A Modern Perspective Advanced Texts in Econometrics; ... Phasing in Crystallography A Modern Perspective Carmelo Giacovazzo. Unique overview of all crystallographic phasing methods today;
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